Mometasone cream

1. Introduction

Mometasone is a medium-to-high potency topical corticosteroid used to treat various inflammatory skin conditions. It reduces redness, swelling, itching, and discomfort caused by dermatological conditions such as eczema, psoriasis, and dermatitis. Mometasone is available in forms such as creams, ointments, and lotions.

2. Indications

  • Atopic dermatitis (eczema)
  • Psoriasis (excluding widespread plaque psoriasis)
  • Seborrhoeic dermatitis
  • Contact dermatitis (allergic or irritant)
  • Lichen planus
  • Discoid lupus erythematosus
  • Other inflammatory skin conditions responsive to corticosteroids

3. Dosage

Adults and Children (≥2 years):

  • Apply a thin layer to the affected area once daily.
  • Duration of use varies depending on the condition; limit use to 2 weeks for large areas or sensitive skin regions (e.g., face, groin).

Children (<2 years):

  • Not recommended unless specifically prescribed by a doctor due to potential risks of systemic absorption.

4. Administration

  • Wash and dry hands before and after application.
  • Apply a thin layer to the affected skin and rub in gently.
  • Do not cover the treated area with occlusive dressings unless directed by your doctor.

5. Forms Available

  • Cream: 0.1%
  • Ointment: 0.1%
  • Lotion: 0.1%
  • Scalp application: 0.1%

6. Side Effects

6.1 Common Side Effects:

  • Skin thinning (with prolonged use)
  • Burning or stinging at the application site
  • Dryness or irritation

6.2 Less Common Side Effects:

  • Folliculitis (inflammation of hair follicles)
  • Hyperpigmentation or hypopigmentation
  • Stretch marks (striae)

6.3 Rare but Serious Side Effects:

  • Systemic absorption leading to adrenal suppression (with prolonged use or large-area application)
  • Skin infections (bacterial, fungal, or viral exacerbation)
  • Allergic contact dermatitis

7. Warnings

  • Prolonged Use: Avoid prolonged use or application to large areas to minimise the risk of systemic absorption.
  • Sensitive Areas: Use sparingly on thin-skinned areas (e.g., face, groin, armpits) due to a higher risk of side effects.
  • Infections: Avoid applying to infected skin unless specifically treated for the infection.

8. Precautions

  • Use with caution in patients with pre-existing skin infections (e.g., impetigo, fungal infections).
  • Do not apply near the eyes, as it may cause glaucoma or cataracts.
  • Avoid use in broken or weeping skin unless advised by a healthcare provider.

9. Interactions

  • Topical Antifungals or Antibiotics: Can be used concurrently but apply at separate times to avoid dilution or interference.
  • Systemic Corticosteroids: Concurrent use may increase the risk of adrenal suppression.

10. Monitoring Parameters

  • Assess skin condition for improvement or signs of adverse effects during treatment.
  • Monitor for signs of skin thinning, striae, or infection.
  • In long-term or high-dose use, consider periodic checks for signs of adrenal suppression.

11. Use in Children

  • Approved for use in children ≥2 years for short durations.
  • Use with caution due to the higher risk of systemic absorption and growth suppression.

12. Use in Pregnancy

  • Considered Category C; use only if the potential benefit outweighs the risks. Prolonged use or application to large areas should be avoided during pregnancy.

13. Use in Elderly

  • Generally well tolerated, but elderly patients may have thinner skin and a higher risk of side effects like skin thinning or bruising.

14. Use in Kidney Disease

  • No specific adjustments are required, as systemic absorption is typically minimal.

15. Use in Liver Disease

  • Use cautiously in severe liver impairment, as systemic absorption may lead to corticosteroid-related effects.

16. Patient Counselling Points

  • Apply a thin layer only to the affected areas as directed by your doctor.
  • Avoid applying to large areas, broken skin, or sensitive regions unless advised.
  • Do not use for longer than prescribed, especially on the face or in children.
  • Report any worsening of skin condition, signs of infection, or unusual side effects like skin thinning.
  • Store the medication at room temperature, away from heat and light.

17. Table of Brand Names, Manufacturer, and Prices in USD

Brand NameManufacturerStrength/Dosage FormPrice (USD)
EloconMerck0.1% Cream$30 (15 g)
Elocon OintmentMerck0.1% Ointment$35 (15 g)
Generic MometasoneVarious0.1% Cream$20 (15 g)

18. 15 FAQs (Frequently Asked Questions)

1. What is Mometasone used for on the skin?
Mometasone is used to treat inflammatory skin conditions such as eczema, psoriasis, and dermatitis.

2. How does Mometasone work?
It reduces inflammation, swelling, and itching by suppressing the immune response in the skin.

3. How often should Mometasone be applied?
Typically, it is applied once daily or as directed by your doctor.

4. Can Mometasone be used on the face?
It can be used sparingly on the face for short durations under medical supervision due to the risk of skin thinning.

5. Is Mometasone safe for children?
Yes, it is safe for children aged 2 years and older, but only for short-term use.

6. Can Mometasone be used during pregnancy?
It should only be used if the benefits outweigh the risks. Prolonged or large-area use should be avoided.

7. Can Mometasone cause skin thinning?
Yes, prolonged or excessive use may lead to skin thinning, especially in sensitive areas.

8. What should I do if I miss a dose?
Apply the missed dose as soon as you remember, but do not double the next application.

9. Can Mometasone worsen infections?
Yes, it can worsen untreated bacterial, fungal, or viral skin infections.

10. How should Mometasone be stored?
Store at room temperature, away from moisture and heat.

11. Can Mometasone be used for acne?
No, it is not recommended for acne and may worsen the condition.

12. How long can I use Mometasone?
Duration varies, but long-term use should be avoided without medical supervision.

13. Can Mometasone cause allergies?
In rare cases, it can cause allergic contact dermatitis. Stop use and consult your doctor if irritation occurs.

14. Can I use moisturisers with Mometasone?
Yes, but apply the moisturiser after Mometasone has been absorbed into the skin.

15. Do I need a prescription for Mometasone?
Yes, Mometasone is a prescription-only medication.