Simple English explanation with example
- It blocks a specific protein that causes migraine pain signals.
- It stops blood vessels in the brain from swelling painfully.
- It can stop a migraine and also prevent future ones.
- The tablet melts on your tongue without needing any water.
- Example: Cutting the wire to a siren before it sounds.
Scientific explanation
- Nurtec (Rimegepant) is a calcitonin gene-related peptide (CGRP) receptor antagonist.
- It binds to CGRP receptors to block the peptide’s binding.
- It inhibits neurogenic inflammation and prevents vasodilation in intracranial vessels.
- This action stops the transmission of pain signals via trigeminal nerves.
- It lacks the vasoconstrictive properties found in older triptan medications.