Simple English explanation with example
- It acts like a dual-action switch for your body’s metabolism.
- The medicine mimics two natural hormones that tell you “I am full.”
- It slows down how fast food leaves your stomach after eating.
- Think of it like a dimmer switch that lowers your sugar levels.
- Example: You eat half a meal and feel naturally satisfied.
Scientific Explanation
- Mounjaro (Tirzepatide) is a dual GIP and GLP-1 receptor agonist.
- It enhances first- and second-phase insulin secretion via pancreatic beta-cells.
- Reduces glucagon secretion from alpha-cells in a glucose-dependent manner.
- Delays gastric emptying to modulate postprandial glucose absorption significantly.
- Increases insulin sensitivity in peripheral tissues via GIP receptor activation.