Simple English explanation with example
- It targets the tiny muscles wrapped around your breathing tubes.
- It forces those muscles to relax and open up immediately.
- This allows more air to move in and out of lungs.
- It is designed to work in minutes during a breathing crisis.
- Example: Unclamping a squeezed straw so you can breathe through it.
Scientific Explanation
- Albuterol (Salbutamol) is a short-acting beta2-adrenergic receptor agonist (SABA).
- It stimulates adenyl cyclase to increase intracellular cyclic AMP levels.
- Activation of protein kinase A leads to smooth muscle relaxation.
- It inhibits the release of bronchoconstricting mediators from pulmonary mast cells.
- Provides rapid bronchodilation (onset < 5 mins) lasting up to 6 hours.