Common: Loss of appetite, insomnia, weight loss, increased heart rate.
Less Common: Dry mouth, headache, jitteriness.
Rare but Serious: Cardiac issues, psychiatric disorders like paranoia or mania, long-term growth suppression in children.
Warnings
Substance Abuse: High potential for abuse and dependence; classified as a Schedule II controlled substance.
Contraindications: Known hypersensitivity to sympathomimetic amines, advanced arteriosclerosis, symptomatic cardiovascular disease, moderate to severe hypertension.
Precautions
General: Monitor growth in children and mental health in all patients.
Health Conditions: Caution in patients with a history of drug dependence or alcoholism.
Interactions
Medications: Avoid concomitant use with MAO inhibitors, certain antidepressants, and antihypertensive medications.
Food: Acidic foods can reduce absorption; avoid large amounts of citrus or vitamin C around dose times.
Monitoring Parameters
Blood Pressure and Heart Rate: Regular checks are necessary.
Growth in Children: Monitor height and weight periodically.
Mental Health: Assess for new or worsening psychiatric symptoms.
Use in Children
Guidelines: Approved for use in children over 3 years old for ADHD.
Monitoring: Essential to monitor side effects, especially growth suppression and mental health changes.
Use in Pregnancy
FDA Category: C. Potential risks should be weighed against potential benefits; not recommended unless necessary.
Use in Elderly
Recommendations: Typically not recommended due to higher cardiovascular risks and other potential side effects.
Use in Kidney Disease
Adjustments: May require lower doses; monitor closely due to potential for decreased clearance.
Use in Liver Disease
Caution: Use with caution; may require dose adjustments depending on the extent of liver impairment.
Patient Counselling Points
Medication Use: Adherence to prescribed doses is crucial; do not adjust dosage without consulting a healthcare provider.
Side Effects: Immediate reporting of cardiac symptoms or signs of psychological changes is essential.
Lifestyle: Dietary recommendations to avoid certain foods that may interact with the drug’s effectiveness.
Table of Brand Names, Manufacturer, and Prices in USD
Brand Name
Manufacturer
Strength/Dosage Form
Price (USD)
Dexedrine
Amedra
10 mg Tablet
$2.80
Zenzedi
Arbor
30 mg Tablet
$4.00
ProCentra
Takeda
5 mg/5 mL Liquid
$5.00
15 FAQs with Answers
What is Dextroamphetamine used for? – Primarily to treat ADHD and narcolepsy.
Can Dextroamphetamine cause addiction? – Yes, it has a high potential for abuse and dependence.
How should Dextroamphetamine be taken? – Take orally, in the morning to avoid insomnia; follow the exact prescription.
What are the common side effects of Dextroamphetamine? – Includes insomnia, weight loss, and increased heart rate.
Is Dextroamphetamine safe during pregnancy? – Category C, generally not recommended unless clearly needed.
Can Dextroamphetamine be taken with alcohol? – Alcohol can increase the risk of side effects; it’s best avoided.
What does Dextroamphetamine interact with? – MAO inhibitors and certain antihypertensive drugs can cause dangerous interactions.
What should I avoid while taking Dextroamphetamine? – Avoid acidic foods and beverages which can impact drug absorption.
What are signs of a Dextroamphetamine overdose? – Symptoms may include rapid breathing, confusion, fever, and restlessness.
Is Dextroamphetamine addictive? – Yes, it is classified as a Schedule II controlled substance due to its potential for abuse.
Should I stop taking Dextroamphetamine suddenly? – Discontinuation should be supervised by a healthcare provider to manage withdrawal symptoms.
What are the rare but serious side effects of Dextroamphetamine? – Includes severe cardiac complications and psychiatric disorders.
What other medications interact with Dextroamphetamine? – Certain antidepressants and antihypertensive medications can have significant interactions.
Who should not take Dextroamphetamine? – Individuals with severe cardiovascular disease, hypertension, or a history of substance abuse.
How does Dextroamphetamine work to treat ADHD? – It increases neurotransmitter activity in the brain, improving attention and reducing impulsivity.