Simple English explanation with example
- It copies a hormone in your gut called GLP-1.
- It tells your brain that you don’t need more food.
- It helps your pancreas release the right amount of insulin.
- It stops the liver from making too much extra sugar.
- Example: Passing by a favorite snack without feeling an urge.
Scientific Explanation
- Ozempic (Semaglutide) is a selective GLP-1 receptor agonist (94% homology).
- It stimulates glucose-dependent insulin secretion through cyclic AMP pathways.
- Suppresses inappropriately elevated glucagon levels, reducing hepatic glucose output.
- The molecule is albumin-bound to extend its half-life to seven days.
- Slows gastric motility by inhibiting vagal nerve signals to the stomach.