Cannabis

Treatment, Dosage, Side Effects, Interactions, Warnings, Pregnancy, Elderly, Renal, Hepatic, Patient Counselling, Pricing, Monitoring Parameters, Age-Specific Use and your FAQs

What Is Cannabis?

  • Cannabis is a plant used for medicinal, recreational, and industrial purposes.
  • Contains active compounds called cannabinoids, including:
    • THC (Tetrahydrocannabinol): Responsible for psychoactive effects (the “high”).
    • CBD (Cannabidiol): Non-psychoactive, known for therapeutic benefits.

How Does Cannabis Work?

  • Cannabinoids interact with the endocannabinoid system (ECS) in the body.
  • ECS helps regulate functions like mood, pain, appetite, and sleep.
  • THC and CBD bind to receptors (CB1 and CB2) to produce various effects.

Uses of Cannabis

Medicinal Uses

  • Chronic Pain: Reduces pain in conditions like arthritis and neuropathy.
  • Anxiety and Depression: Helps manage symptoms, though high doses of THC may worsen anxiety.
  • Epilepsy: CBD-based medications (e.g., Epidiolex) reduce seizures in severe epilepsy.
  • Cancer: Alleviates nausea and vomiting from chemotherapy and stimulates appetite.
  • Multiple Sclerosis (MS): Reduces muscle spasticity.
  • Glaucoma: Lowers intraocular pressure, though its effects are short-lived.

Recreational Uses

  • Used for relaxation, euphoria, and sensory enhancement.
  • Legal for recreational use in some regions, subject to local laws.

Forms of Cannabis

  • Dried Flower: Smoked or vaporized.
  • Oils and Tinctures: Consumed sublingually (under the tongue).
  • Edibles: Infused foods and beverages with delayed effects.
  • Topicals: Creams and balms for localized pain relief.
  • Capsules/Tablets: Controlled dosages for medicinal use.

Dosage and Administration

  • Start with a low dose and increase gradually (especially for THC).
  • Effects vary based on:
    • Form of cannabis.
    • Route of administration (inhalation vs. ingestion).
    • Individual factors like weight and tolerance.
  • Typical onset and duration:
    • Inhalation: Effects within minutes, lasting 2-4 hours.
    • Edibles: Effects within 30-90 minutes, lasting 6-8 hours.

Potential Benefits of Cannabis

  • Pain relief without the risks of opioid addiction.
  • Improved sleep for insomnia patients.
  • Anti-inflammatory properties for chronic conditions.
  • Reduced seizure frequency in epilepsy patients.

Precautions Before Using Cannabis

  • Medical History: Inform your doctor if you have:
    • Heart disease (THC can increase heart rate).
    • A history of mental health conditions like psychosis.
    • Liver or kidney disease.
  • Pregnancy and Breastfeeding: Avoid cannabis due to potential risks to the baby.
  • Drug Interactions:
    • May interact with blood thinners like warfarin.
    • Use caution with sedatives, as cannabis can enhance their effects.

Possible Side Effects

Short-Term Side Effects

  • Dry mouth and red eyes.
  • Increased heart rate.
  • Drowsiness or dizziness.
  • Impaired memory and coordination.
  • Anxiety or paranoia (at high doses of THC).

Long-Term Side Effects

  • Dependence or addiction in some users.
  • Respiratory issues from smoking.
  • Cognitive impairment with prolonged heavy use, especially in adolescents.

Serious Risks

  • Psychosis or schizophrenia in predisposed individuals.
  • Cannabinoid Hyperemesis Syndrome (CHS): Cyclic vomiting from chronic use.

Legal Status of Cannabis

  • Laws vary globally.
  • In many countries, cannabis is legalized or decriminalized for:
    • Medicinal Use: Requires a doctor’s prescription.
    • Recreational Use: Subject to age and purchase limits.
  • Always check local regulations before use.

FAQs About Cannabis

Q1: Is cannabis addictive?

  • Cannabis has a low risk of addiction, but frequent use can lead to dependence in some individuals.

Q2: Can cannabis cure diseases?

  • Cannabis does not cure diseases but can help manage symptoms like pain, nausea, and seizures.

Q3: How long does cannabis stay in your system?

  • THC can be detected in urine for days to weeks, depending on usage frequency.

Q4: Is CBD legal everywhere?

  • CBD derived from hemp with less than 0.3% THC is legal in many countries but may still be restricted in some regions.

Q5: Can I drive after using cannabis?

  • No. Cannabis impairs reaction time and judgment, increasing the risk of accidents.

Q6: What is the difference between THC and CBD?

  • THC is psychoactive and causes a “high,” while CBD is non-psychoactive and focuses on therapeutic effects.

Q7: Can cannabis cause withdrawal symptoms?

  • Yes, symptoms like irritability, insomnia, and reduced appetite may occur after stopping heavy use.

Storage

  • Store in a cool, dark place away from heat and moisture.
  • Keep out of reach of children and pets.
  • Ensure proper labeling to avoid accidental use.

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