How Metformin Works

How a medicine actually work, it’s pathophysiology and pharmacology – in simple English with example followed by the scientific language.

Reviewed: 1 Jan 2026 • Next Review: 1 Jan 2027 • Source: FDA – SmPC – WHO • Suggest an edit

Professional & Patient Guide

Clinical Reviewer: S Chishti MRPharmS (UK)

Educational purpose only

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Simple English explanation with example

Lowers blood sugar levels
Reduces sugar production in liver
Improves insulin sensitivity
Used in type 2 diabetes
Example: keeps sugar stable after meals

Scientific explanation

Decreases hepatic gluconeogenesis
Improves insulin sensitivity
Activates AMPK pathway
Reduces intestinal glucose absorption
First-line diabetes therapy

AI Pharmacist helps your understanding. For diagnosis, treatment decisions, or changing medicines, please speak to a registered pharmacist or doctor in your country.

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