Simple English explanation with example
- It blocks a specific protein that helps blood turn solid.
- It keeps the blood flowing smoothly like a liquid stream.
- This prevents dangerous clots from forming in the heart or legs.
- It works quickly and doesn’t require constant blood test checks.
- Example: Adding a thinner to paint to stop it from clumping.
Scientific Explanation
- Eliquis (Apixaban) is an oral, highly selective Factor Xa inhibitor.
- It inhibits both free and clot-bound Factor Xa activity directly.
- Prevents the conversion of prothrombin to thrombin in the coagulation cascade.
- Decreases thrombin-stimulated platelet aggregation without requiring an antithrombin III cofactor.
- Maintains a predictable pharmacokinetic profile with minimal food or drug interactions.